Posters
Electronic Genome Mapping for Verifying Somatic Structural Variants
Structural variants (SVs) are critical drivers of cancer initiation, progression, and therapeutic resistance. Yet, verifying larger SVs—beyond 300 base pairs—remains difficult using sequencing or cytogenetic methods alone.
This poster demonstrates how Electronic Genome Mapping (EGM) on the OhmX™ Platform independently verified hundreds of high-confidence somatic SVs in tumor-derived cell lines, including complex insertions and deletions.
Key insights from the poster:
- Independent validation of SVs across a wide size range, from 300 bp to several megabases
- High concordance with long-read sequencing, while confirming difficult-to-validate variants
- Use of ultra-long, native double-stranded DNA for improved accuracy
- A streamlined, cost-effective workflow suitable for translational cancer research
By serving as a powerful complementary technology, EGM strengthens confidence in somatic SV analysis and advances the study of cancer genomics.
Download the poster now to explore how EGM delivers reliable verification of structural variants.
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Cancer Research
Gain deeper insights and drive breakthroughs in cancer research with the OhmX™ Platform, powered by electronic genome mapping (EGM) and expertly engineered to unravel the complexities of structural variants (SVs) in cancer genomes.
Orthogonal Validation of NGS and LRS
Gain confidence in your genomic discoveries from NGS and long-read sequencing (LRS) platforms with a low-cost solution to verify, clarify, and identify structural variant (SV) calls.
Rare Disease
Unravel complexities and gain critical insights with the OhmX™ Platform, designed to help you push the boundaries of rare disease research.
Cell and Gene Therapy
EGM provides clarity to genomic integrity where other tools can’t.