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Genome Prep

The OhmX Analyzer streamlines SV detection with a fast, user-friendly workflow.

From Sample to Injection, in a Single Day

Streamline structural variant detection with fast, amplification-free DNA analysis

The OhmX VOLT™ Whole Genome Kit workflow provides a seamless path from DNA to valuable insights on the OhmX Platform. Go from cells to injection in just one day using the workflow’s user-friendly standard molecular biology techniques, and without the need for additional equipment. Our workflow is amplification-free, making unbiased, genome-wide structural variant (SV) detection easier than ever.

2 Hours

Hands-on time, one-day workflow

End-to-End

Simple, plug-and-play implementation

Whole Genome

Unique chemistry enables dense, full genome tagging

Expedite Your Research With a Broader Range of SVs

A flexible chemistry, for whole genome analysis

Expedite your research and detect a broadened range of structural variants with electronic genome mapping, starting with an easy to follow sample preparation workflow.

Accessible Design

‍Designed for accessibility and ease of use, the OhmX Platform leverages standard molecular biology techniques, making the process is user-friendly for anyone in your lab, and doesn’t require additional lab equipment or specialized training.

Adaptive Workflow

‍The flexible protocol contains multiple convenient stopping points and the ability to store the OhmX-ready sample for up to two weeks so you can plan your experiments at your convenience—allowing you to adapt your workflow to your research needs.

Rapid Insights

‍The entire sample preparation process takes just one day, significantly reducing the time required for your research and enabling you to generate insights and results more rapidly.

Sample Types

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DNA Isolation

Reliable yields of HMW DNA in just 60 minutes

The NEB® Monarch® HMW DNA Extraction Kit for Cells & Blood #T3050 has been optimized for use on the OhmX Platform for our HMW DNA extraction workflow.

This streamlined ~60-minute protocol allows you to map long-range HMW DNA molecules of 50–500 kb and and yields more than 5 μg of pure HMW DNA with flexible input requirements of only ~1 million cells or 200–500 µL of blood.

DNA Tagging

High-density tagging for genome insights

The OhmX VOLT™ Whole Genome Kit simplifies DNA preparation by employing sequence-specific nicking enzymes. These enzymes precisely label and tag High Molecular Weight (HMW) DNA at known recognition sites, typically spaced every ~4 kb.

Subsequently, tagged DNA molecules are electronically detected by the OhmX Detector as they traverse nanochannels, generating a precise, genome-wide map.

Nabsys' proprietary tagging technique significantly enhances data resolution. It enables the addition of 20% more tags to the DNA compared to other mapping technologies, thus providing highly efficient and detailed insights into structural variations and genomic abberations.